SlackBuilds Repository

14.1 > Academic > cistrome-MACS (1.4.2)

MACS: Model-based Analysis of ChIP-Seq

Next generation parallel sequencing technologies made chromatin
immunoprecipitation followed by sequencing (ChIP-Seq) a popular
strategy to study genome-wide protein-DNA interactions, while creating
challenges for analysis algorithms. We present Model-based Analysis of
ChIP-Seq (MACS) on short reads sequencers such as Genome Analyzer
(Illumina / Solexa). MACS empirically models the length of the
sequenced ChIP fragments, which tends to be shorter than sonication or
library construction size estimates, and uses it to improve the
spatial resolution of predicted binding sites. MACS also uses a
dynamic Poisson distribution to effectively capture local biases in
the genome sequence, allowing for more sensitive and robust
prediction. MACS compares favorably to existing ChIP-Seq peak-finding
algorithms, is publicly available open source, and can be used for
ChIP-Seq with or without control samples.

Maintained by: Petar Petrov
Keywords: biology,ChIP,cistrome

Homepage:
http://liulab.dfci.harvard.edu/MACS/

Source Downloads:
MACS-1.4.2-1.tar.gz (950dab09fe1335c8bbb34a896c21e3e2)

Download SlackBuild:
cistrome-MACS.tar.gz
cistrome-MACS.tar.gz.asc (FAQ)

(the SlackBuild does not include the source)

See our HOWTO for instructions on how to use the contents of this repository.

Access to the repository is available via:
ftp git cgit http rsync

[  Exec: 0.0287 sec  |  Load: 0.06 0.06 0.05  ]

© 2006-2014 SlackBuilds.org Project. All rights reserved.
Slackware® is a registered trademark of Patrick Volkerding
Linux® is a registered trademark of Linus Torvalds
Web Design by WebSight Designs |  Managed Hosting by OnyxLight Communications